在线客服系统
 
招聘信息  |  中文版  |  ENGLISH
    首页 > 产品
    快速导航
  重点推荐
  GastroPlus药代及制剂模拟软件
  ADMET性质预测 ADMET Predictor
  体外溶出模拟平台DDDPlus
  药物筛选、设计、优化
  数据挖掘与药物设计软件
  化学结构绘制软件-免费
  药物制剂
  制剂体外溶出模拟平台
  GastroPlus药代及制剂模拟软件
  安全评价与毒代研究
  毒性与代谢产物预测软件
  DMPK与临床药理
  生理药动PBPK软件
  仿制药一致性评价
  定制开发产品
  实验试剂及耗材
 
胃肠道试剂

膜渗透内标剂

 

本品提供了一系列的渗透特征的内标物,包括高渗透、中等渗透、低渗透的化合物;可结合渗透内标剂,快速评价化合物的膜渗透特征,为进一步评价化合物的吸收行为奠定基础。

 

应用中,可选择不同行为的内标剂进行标准曲线的绘制和校正,然后在此基础上,滴加适当浓度的所评化合物,便可短时间内得出该化合物的膜渗透特征。内标剂采用了最严格的工艺管理,满足FDAGLP规范,所有内标剂的曲线校正均与临床数据进行了比对,用户可放心使用,定可得出最为准确的实验数据。

 

Internal standard agent for membrane permeability

 

This agent provides a series of compounds which have different permeability. The agent includes compounds which have high permeability, medium permeability and low permeability. The user can rapidly get the membrane permeability of the evaluated compound based on this agent. Then this value can evaluate the absorption behaviour of the compound.

 

In practice, the user can select different internal agents to draw a standard curve. Then appropriate concentration of evaluation compound would be added into the culture dish. After it, the membrane permeability of evaluated compound can be measured in a short time. This agent is produced in the most strict process management, and the process is also meet to the GLP guidance in FDA. And all standard curves of internal agents are compared with clinical PK data. The user can feel free to use and most important, the accurate experiment data will be obtained when use this agent.

 

 

 

 

 

 

肠道吸收试剂盒

 

该试剂盒是基于BCS分类系统的理论研制而来,可为用户提供评价化合物BCS分类、肠道吸收百分数等特征参数进行指导。基于该试剂盒,用户可评价得到在FDACFDA法规政策中BCS分类,进行评价化合物的溶解、溶出和吸收特征。可得到BCS分类系统的三个特征参数,剂量分类、溶出分数和吸收分数,并结合这三个参数的结果进一步评估得到化合物在人体的口服吸收百分数。为准确评估化合物的BCS分类以及胃肠道的吸收行为提供参考依据。

 

Intestinal Absorption Kit

 

This kit is developed based on the theory of BCS classification system. It can provide a method to evaluate BCS classification of compounds, fraction of absorption in the intestinal tract and so on.

 

Based on this kit, the user can evaluate the solubility, dissolution and absorption of his compound, BCS classification is also can be got in the standard of FDA or CFDA guidance. The results can get three nondimensional numbers including dose number, dissolution and absorption number. And then it can be combined with these three parameters to further evaluate human oral fraction of the compound. This can provide some references for assessment the compound BCS classification and absorption behavior in GI tract.