在线客服系统
 
招聘信息  |  中文版  |  ENGLISH
    首页 > 新闻中心
    快速导航
  公司简介
  公司动态
  合作伙伴
 
采用ADMET Predictor发表的部分文献(2015.7-2016.6)
2016-09-05

采用ADMET Predictor发表的部分文献(2015.7-2016.6

2015年7月至2016年6月,研究人员采用ADMET Predictor 发表了近百篇文章,

我们节选了其中的85篇,供您参考

 

001  BDDCS, the Rule of 5 and drugability. IF=15.606
Benet LZ, Hosey CM, Ursu O, Oprea TI. (2016) Adv. Drug Delivery Reviews, 101, 89-98.

002 Pore blocking: An innovative formulation strategy for the design of alcohol resistant multi-particulate dosage forms.    IF=3.994
Schrank S, Jedinger N, Wu S, Piller M, Roblegg E. (2016) Int. J. Pharm.509, 219-228. 

003Design, Synthesis, and Biological Evaluation of Novel PARP-1 Inhibitors Based on a 1H-Thieno[3,4-d] Imidazole-4-Carboxamide Scaffold.    IF=2.465
Wang L, Liu F, Jiang N, Zhou W, Zhou X, Zheng Z. (2016) Molecules , 21(6), 772. 

004 Computational.prediction.of.formulation.strategies.for.beyond-rule-of-5compounds. IF=15.606
Bergstrom CAS, Charman WN, Porter CJH. (2016) Adv. Drug Delivery Reviews, online Feb. 27.

005 In Silico Models for Acute Systemic Toxicity.   
Burton J, Worth AP, Tsakovska I, Diukendjieva, A. (2016) In "In Silico Methods for Predicting Drug Toxicity, for the series Methods in Molecular Biology", ed. Emilio Benfenati, published by Springer New York. 

006 In Silico Prediction of Chemically Induced Mutagenicity: How to Use QSAR Models and Interpret Their Results.     
Mombelli E, Raitano G, Benfenati E. (2016) In "In Silico Methods for Predicting Drug Toxicity, for the series Methods in Molecular Biology", ed. Emilio Benfenati, published by Springer New York. 

007 Descriptors and their selection methods in QSAR analysis: paradigm for drug design.     IF=5.625
Danishuddin, Khan AU. (2016) Drug Discovery Today, July. 

008 High-throughput virtual screening and quantum mechanics approach to develop imipramine analogues as leads against trypanothione reductase of leishmania.     IF=2.326
Pandey RK, Verma P, Sharma D, Bhatt TK, Sundar S, Prajapati VK. (2016) Biomedicine & Pharmacotherapy, 83, 141-152. 

009 Evaluating the Impact of Uncertainties in Clearance and Exposure When Prioritizing Chemicals Screened in High-Throughput Assays.     IF=5.393
Leonard JA , Leonard AS, Chang D, Edwards S, Lu J, Scholle S, Key P, Winter M, Isaacs KK, Tan YC. (2016) Environ. Sci. Technol., online April 28.

010 Comparative human in-vivo study of an immediate release tablet over-encapsulated by gelatin and hydroxypropyl methyl cellulose capsules – impact of dissolution rate on bioequivalence.    IF=1.944
Stegemann S, Vishwanath S, Kumar R, Cade D, Lowery M, Hutchison K, Michael Morgen M, Goodwin A, Lee C.(2016) Capsugel white paper.

011 Structure-based virtual screening, molecular docking, ADMET and molecular simulations to develop benzoxaborole analogs as potential inhibitor against Leishmania donovani trypanothione reductase.   IF=1.782
Pandey RK, Kumbhar BV, Sundar S, Kunwar A, Prajapati VK. (2016) J. Receptors and Signal Transduction. 

012 Integration of Life-Stage Physiologically-Based Pharmacokinetic (PBPK) Models with Adverse Outcome Pathways (AOPs) and Environmental Exposure Models to Screen for Environmental Hazards.     IF=3.88
El-Masri H, Kleinstreuer N, Hines RN, Adams L, Tal T, Isaacs K, Wetmore BA, Tan Y. (2016), Tox. Sci., online May 4. 

013 In silico screening of novel inhibitors of M17 Leucine Amino Peptidase (LAP) of Plasmodium vivax as therapeutic candidate.     IF=2.326
Rout S, RK Mahapatra RK. (2016) Biomedicine & Pharmacotherapy, 82, 192-201. 

014High throughput virtual screening and in silico ADMET analysis for rapid and efficient identification of potential PAP248-286 aggregation inhibitors as anti-HIV agents. IF=1.78
Malik R, Bunkar D, Choudhary BS, Srivastava S, Mehta P, Sharma M. (2016) J. Mol. Struct., 1122, 239-246.

015 Impact of curcumin on the pharmacokinetics of rosuvastatin in rats and dogs based on the conjugated metabolites.     IF=1.723
Zhou X, Zhang F, Chen C, Guo Z, Liu J, Yu J, Xu Y, Zhong D, Jiang H. (2016) Xenobiotica, online May 13. 

016 Synthesis and Preclinical Evaluation of Sulfonamido based [11C-Carbonyl]-Carbamates and Ureas for Imaging Monoacylglycerol Lipase.    
Wang L, Mori W, Cheng R, Yui J, Hatori A, Ma L, Zhang Y, Rotstein BH, Fujinaga M, Shimoda Y, Yamasaki T, Xie L, Nagai Y, Minamimoto T, Higuchi M, Vasdev N, Zhang M, Liang SH. (2016) Theranositcs, 6(8), 1145-1159. 

017 Development of In Vitro In Vivo Correlation Models For Clopidogrel Tablets To Describe Administration Under Fasting And Fed Conditions.    IF=1.162
Savu SN, Silvestro L, Mirioiu C, Anuta V. (2016) Farmacia, 64, 2. 

018 Introduction to Cheminformatics.     
Wishart DS. (2016) Current Protocols in Bioinformatics, published online: March 24.

019 Quantitative structure-retention relationship of selected imidazoline derivatives on alpha1-acid glycoprotein column.    IF=3.169
Filipic S, Ruzic D, Vucicevic J, Nikolic K, Agbaba D. (2016) J. Pharm. Biomed. Analysis, online March 3.

020Modeling ADMET.
Ghosh J, Lawless MS, Waldman M, Gombar V, Fraczkiewicz R. (2016) In "In Silico Methods for Predicting Drug Toxicity, for the series Methods in Molecular Biology", ed. Emilio Benfenati, published by Springer New York. 

021 Novel nonquaternary reactivators showing reactivation efficiency for soman-inhibited human acetylcholinesterase.    IF=3.522
Wei Z, Liu Y, Wang Y, Li W, Zhou X, Zhao X, Zhao J, Huang C, Li X, Liu J, Zheng Z, Li S. (2016) Toxicology Letters, 246, 1-6.

022 Synthesis and Evaluation of Novel Radioligands Based on 3-[5-(Pyridin-2-yl)-2H-tetrazol-2-yl]benzonitrile for Positron Emission Tomography Imaging of Metabotropic Glutamate Receptor Subtype 5.    IF=3.902
Shimoda Y, Yamasaki T, Fujinaga M, Ogawa M, Kurihara Y, Nengai N, Kumata K, Yui J, Hatori A, Xie L, Zhang Y, Kawamu K, Zhang M. (2016) J. Med. Chem., 59 (8), 3980–3990.

023 Exploring dual inhibitory role of febrifugine analogues against Plasmodium utilizing structure-based virtual screening and molecular dynamic simulation.    IF=2.3
Pandey RK, Narula A, Naskar M, Srivastava S, Verma P, Malik R, Shah P, Prajapatia VK. (2016) J. Biomolecular Structure and Dynamics, published online: April 18.

024 In vitro and in vivo evaluations of the P-glycoprotein-mediated efflux of dibenzoylhydrazines.   IF=3.847
Miyataa K, Nakagawa Y, Kimura Y, Ueda K, Akamatsua M. (2016) Toxiclogy and Applied Pharmacology, 298, 40-47.

025 Novel S1P1 receptor agonists – Part 5: From amino-to alkoxy-pyridines.    IF=3.902
Bolli MH, Lescop C, Birker M, de Kanter R, Hess P, Kohl C, Nayler O, Rey M, Sieber P, Velker J, Weller T, Steiner B. (2016) Eur. J. Med. Chem., 115, 326-341.

026 Provenance of Computers in Pharmacy.    IF=3.83
Bandameedi R. (2016) Clin Pharmacol Biopharm, 5:153.

027 Pharmacokinetic evaluation of cefdinir-loaded floating alginate beads in rabbits using LC–MS/MS. IF=3.994
Praveen R, Singh SK, Ranjan P, Verma P. (2016) J. Pharm. Invest. Online March 5.

028 Development of a Physiologically Based Pharmacokinetic/Pharmacodynamic Model to Predict the Impact of Genetic Polymorphisms on the Pharmacokinetics and Pharmacodynamics Represented by Receptor/Transporter Occupancy of Central Nervous System Drugs.     IF=4.829
Alqahtani S, Kaddoumi A. (2016) Clinical Pharmacokinetics, online February 25.

029 New design of nucleotide excision repair (NER) inihibitors for combination cancer therapy.    IF=1.674
Gentile F, Tuszynskia JA, Barakat KH. (2016) J. Mol. Graphics and Modeling, 65, 71-82.

030 Use of Modeling and Simulation Tools for Understanding the Impact of Formulation on the Absorption of a Low Solubility Compound: Ciprofloxacin.     IF=3.819
Marilyn Martinez M, Mistry B, Lukacova V, Polli J, Hoag S, Dowling T, Kona R, Fahmy R.(2016) AAPS J. Online April 26.

031 In vivo in silico pharmacokinetic simulation studies of carvedilol-loaded nanocapsules using GastroPlus™.
George JK, Singh SK, Verma PRP.(2016) Therapeutic Delivery, 7(5), 305-318.

032 Characterizing the Dissolution Profiles of Supersaturable Salts, Cocrystals, and Solvates to Enhance In Vivo Oral Absorption.    IF=3.975
Hisada N, Takano R, Takata N, Shiraki K, Ueto T, Tanida S, Kataoka M, Yamashita S.(2016) Eur J Pharm Biopharm. Online April 7.

033 Software and Web Resources for Computer-Aided Molecular Modeling and Drug Discovery.    
Yadav DK, Rai R, Pratap R, Singh H.(2016) Chemometrics Applications and Research: QSAR in Medicinal Chemistry, ed. By Andrew G. Mercader, Pablo R. Duchowicz, and PM Sivakumar.

034 Advantage of the Dissolution/Permeation System for Estimating Oral Absorption of Drug Candidates in the Drug Discovery Stage.    IF=4.342
Miyaji Y, Fujii Y, Takeyama S, Kawai Y, Kataoka, M‡, Takahashi M, Yamashita S.(2016) Mol. Pharmaceutics, 13 (5), pp 1564–1574.

035 Identification of Novel Potential Inhibitors of Aldose Reductase: A Multistage Computational Filtering Approach.    
Joseph JM, Kesherwani M, Velmurugan D. (2016) Recent Advance in Diabetes Treatment, Avid Science, ebook.

036 Physiologically Based Absorption Modeling to Impact Biopharmaceutics and Formulation Strategies in Drug Development—Industry Case Studies.    IF=2.641
Kesisoglou F, Chung J, van Asperen J, Heimbach T. (2016) J. Pharmaceutical Sciences, online 23 Jan.

037 LC-ESI-MS/MS estimation of loratadine-loaded self-nanoemulsifying drug delivery systems in rat plasma: Pharmacokinetic evaluation and computer simulations by GastroPlus™.    IF=3.169
Verma S, Singh SK. (2016) Journal of Pharmaceutical and Biomedical Analysis, 124, 10-21.

038 Estimating Margin of Exposure to Thyroid Peroxidase Inhibitors Using High-throughput In Vitro Data, High-throughput Exposure Modeling, and Physiologically-Based Pharmacokinetic/Pharmacodynamic Modeling. IF=3.88
Leonard JA, Tan Y, Gilbert M, Isaacs K, El-Masri, H. (2016) Toxicological Sciences, 151, 57-70.

039 Design.and.synthesis.of.some.new1-phenyl-3/4-[4-(aryl/heteroaryl/alkyl-piperazine1-yl)-phenyl-ureas as potent anticonvulsant and antidepressant agents.    IF=2.49
Mishra CB, Kumari S, Tiwar M. (2016) Archives of Pharmacal Research, online February 18.

040 Acute Toxicity Tests: Tools for Assessment of Toxicological Effects of Plants.  
Balogun ST, Sandabe UK, Jibrin J, Ibrahim E, Fehintola FA. (2016) International Journal of Indigenous Medicinal Plants, ISSN: 2051-4263, Vol.48, Issue 1.

041 Predicting biopharmaceutical performance of oral drug candidates–Extending the Volume to Dissolve Applied Dose concept    IF=3.975
Muenster U, Mueck W, van der Mey D, Schlemmer K, Greschat-Schade S, Haerter M, Pelzetter C, Pruemper C, Verlage J, Goeller AH, Ohm A. (2016) Euro. J. Pharm. And Biopharm., available online March 5.

042 Development of 3,5-Dinitrobenzylsulfanyl-1,3,4-Oxadiazoles and Thiadiazoles as Selective Antitubercular Agents Active Against Replicating and Nonreplicating Mycobacterium tuberculosis   IF=3.902
Karabanovich G, Zemanová J, Smutný T, Székely R, Šarkan M, Centárová I, Vocat A, Pávková I, Conka P, Nemecek J, Stolaríková J, Vejsová M, Vavrova K, Klimešová V, Hrabalek A, Pavek P, Cole ST, Mikušová K, and Roh J. (2016) J. Med. Chem. web pub. Date March 5.

043Radiosynthesis.and.evaluation.ofN-(3,4-dimethylisoxazol-5-yl)piperazine-4-[4-(4-fluorophenyl)thiazol-2-yl]-1-[11C]carboxamide for in vivo positron emission tomography imaging of fatty acid amide hydrolase in brain. IF=3.289
Shimoda Y, Yui Y, Zhang Y, Hatori A, Ogawa M, Fujinaga M, Yamasaki T, Xie L, Kumata K, Zhang MR. (2015) RSC Adv., 5, 106122-106127.

044 Chromatographic lipophilicity as a predictor of antiproliferative activity of 17-picolyl and 17-picolinylidene androstane derivatives toward prostate cancer.    IF=1.32
Kovacevic SZ, Podunavac-Kuzmanovic SO, Jevric LR, Djurendic EA, Ajdukovic JJ, Jovanov PT. (2015) APTEFF, 46, 1-269. 

045 Evaluations of imidazolium ionic liquids as novel skin permeation enhancers for drug transdermal delivery. IF=1.566
Zhang D, Wang H, Cui X, Wang C. (2016) Pharmaceutical Development and Technology, published online Jan 13. 

046 Discovery of novel S1P 2 antagonists, part 3: Improving the oral bioavailability of a series of 1, 3-bis (aryloxy) benzene derivatives.    IF=2.486
Kusumia K, Shinozakib K, Yamauraa Y, Hashimotoa A, Kurataa H, Naganawaa A, Otsukia K, Matsushitaa T, Sekiguchia T, Kakuuchia A, Yamamoto H, Seko T. (2016) Bioorg. & Med. Chem. Lett., 26(4), 1209-1213. 

047 Ferulic acid-carbazole hybrid compounds: combination of cholinesterase inhibition, antioxidant and neuroprotection as multifunctional anti-Alzheimer agents.    IF=2.486
Fang L, Chen M, Liu Z, Fang X, Gou S, Chen L. (2016) Bioorg. & Med. Chem. Lett., 24(4), 886-893. 

048 Febrifugine analogues as Leishmania donovani trypanothione reductase inhibitors: binding energy analysis assisted by molecular docking, ADMET and molecular dynamics simulation.    IF=2.3
Pandey RK, Kumbhar BV, Srivastava S, Malik R, Sundar S, Kunwar A, Prajapati VK. (2016) Journal of Biomolecular Structure and Dynamics, online 3 Jan. 

049 A Study on in-silico Analysis of Phytochemicals targeting the proteins of Hepatitis B and C Virus.   
Vani GS and Rajarajan S. (2015) Int.J.Curr.Microbiol.App.Sci 4(12): 683-691. 

050
Development of a unified dissolution and precipitation model and its use for the prediction of oral drug absorption.    IF=4.342
Jakubiak P, Wagner B, Grimm HP, Petrig-Schaffland J, Schuler F, and Alvarez-Sanchez R. (2016) Mol. Pharm., 13(2), 586-598. 

051
N-(3,4-Dimethylisoxazol-5-yl)piperazine-4-[4-(2-fluoro-4-[11C]methylphenyl) thiazol-2-yl]-1-carboxamide: a promising positron emission tomography ligand for fatty acid amide hydrolase.    IF=2.486
Shimoda Y, Fujinaga M, Hatori A, Yui J, Zhang Y, Nengaki N, Kurihara Y, Yamasaki T,Xie L, Kumata K, Ishiia H, Zhang M. (2016) Bioorg. & Med. Chem., 24(4), 627-634.

 

052 Tales from the war on error: the art and science of curating QSAR data.   IF=3.199
Waldman M, Fraczkiewicz R, and Clark RD. (2015) J Comput Aided Mol Des. 29(9), 897-910.

053 Discovery of new acetylcholinesterase inhibitors with small core structures through shape-based virtual screening    IF=2.486
Chen Y, Liu Z, Fu T, Li W, Xu X, Sun H. Bioorg. & Med. Chem. Lett., 2015, 25, 3442-3446.

054 Assessment of in silico models for acute aquatic toxicity towards fish under REACH regulation.  IF=1.596
Cappelli CI, Cassano A, Golbamaki A, Lombardo A,Colafranceschi M, Benfenati E. SAR and QSAR in Environmental Research, online Nov. 2015.

055 Benzazaborinines as novel bioisosteric replacements of naphthalene: propranolol as an example.  IF=5.447
Rombouts FJR, Tovar F, Austin N, Tresadern G, Trabanco AA. J. Med. Chem., Just Accepted Manuscript, Nov. 13, 2015.

056 Pharmacologic Activities of 3'-Hydroxypterostilbene: Cytotoxic, Anti-Oxidant, Anti-Adipogenic, Anti-Inflammatory, Histone Deacetylase and Sirtuin 1 Inhibitory Activity.    IF=2.59
Takemoto JK, Remsberg CM, Davies NM. J. Pharm. Pharm. Sci 18(4) 713-727, 2015

057 Analysis of Intra- and Intersubject Variability in Oral Drug Absorption in Human Bioequivalence Studies of 113 Generic Products.    
Sugihara M, Takeuchi S, Sugita M, Higaki K, Kataoka M,Yamashita S. Mol. Pharmaceutics, Article ASAP Nov. 15, 2015. 

058 Tools for early prediction of drug loading in lipid-based formulations.   IF=4.384
Alskar LC, Porter CJH, Bergstrom CAS. Mol. Pharmaceuticals, web., Nov. 15, 2015.

059 A review of the current state of the art of physiologically-based tests for measuring human dermal in vitro bioavailability of polycyclic aromatic hydrocarbons (PAH) in soil.    IF=4.529
Beriro DJ, Cave MR, Wragg J, Thomas R,Wills G, Evansc F. J. Hazardous Materials, Available online 18 November 2015. 

 

060 Tales from the war on error: the art and science of curating QSAR data.    IF= 3.199
Waldman M, Fraczkiewicz R, and Clark RD. (2015) J Comput Aided Mol Des. 29(9), 897-910.

061 Assessment of in silico models for acute aquatic toxicity towards fish under REACH regulation. IF= 1.897
Cappelli CI, Cassano A, Golbamaki A, Lombardo A,Colafranceschi M, Benfenati E. SAR and QSAR in Environmental Research, online Nov. 2015.

062 Benzazaborinines as novel bioisosteric replacements of naphthalene: propranolol as an example. IF= 5.589
Rombouts FJR, Tovar F, Austin N, Tresadern G, Trabanco AA. J. Med. Chem., Just Accepted Manuscript, Nov. 13, 2015.

063 Pharmacologic Activities of 3'-Hydroxypterostilbene: Cytotoxic, Anti-Oxidant, Anti-Adipogenic, Anti-Inflammatory, Histone Deacetylase and Sirtuin 1 Inhibitory Activity.   IF= 2.59
Takemoto JK, Remsberg CM, Davies NM. J. Pharm. Pharm. Sci 18(4) 713-727, 2015 

064 Analysis of Intra- and Intersubject Variability in Oral Drug Absorption in Human Bioequivalence Studies of 113 Generic Products.    IF=4.342
Sugihara M, Takeuchi S, Sugita M, Higaki K, Kataoka M,Yamashita S. Mol. Pharmaceutics, Article ASAP Nov. 15, 2015.

065 Tools for early prediction of drug loading in lipid-based formulations.  
Alskar LC, Porter CJH, Bergstrom CAS. Mol. Pharmaceuticals, web., Nov. 15, 2015.

066 A review of the current state of the art of physiologically-based tests for measuring human dermal in vitro bioavailability of polycyclic aromatic hydrocarbons (PAH) in soil.     IF=4.836
Beriro DJ, Cave MR, Wragg J, Thomas R,Wills G, Evansc F. J. Hazardous Materials, Available online 18 November 2015.

067 The use of computational chemistry to predict toxicity of antioxidants food additives and its metabolites as a reference for food safety regulation.     IF=6.567
Damayanti S, Permana J, Tjahjono DH. Der Pharma Chemica, 2015, 7(9):174-181.

068 Novel derivatives of nitro-substituted salicylic acids: Synthesis, antimicrobial activity and cytotoxicity.
Paraskevopoulos G,Krátký M,Mandíková J, Trejtnar F, Stolaríková J, Pávek P,Besra G, Vinšová J. Bioorg. and Med. Chem., Available online 24 October 2015.

069 In vitro anticancer properties and biological evaluation of novel natural alkaloid jerantinine B. IF=5.992
Qazzaz ME, Raja VJ, Lim K, Kam T, Lee JB, Gershkovich P, Bradshaw TD. Cancer Letters, online Oct. 26, 2015.  

070 The evolution and future of environmental partition coefficients.   
Mackay D, Celsie AKD, Parnis JM. Environmental Reviews, published on the we 04 Novem bber 2015.

071 Discovery of New Scaffolds from Approved Drugs as Acetylcholinesterase Inhibitors IF=2.45
Chen, Y, Xu X, Fu T, Li W, Liu Z, Sun H. RSC Adv., 2015,5, 90288-90294.

072 Development of Physiologically Based Pharmacokinetic/Pharmacodynamic Model for Indomethacin Disposition in Pregnancy.   IF=3.057
S Alqahtani, A Kaddoumi , PLOS One, October 2015.

073 Role of computer-aided drug design in modern drug discovery.   IF=2.49
Macalino, SJY, Gosu V, Hong S, and Cho S. (2015) Archives of Pharmacal Research 38(9), 1686-1701.

074 Lipidic dispersion to reduce food dependent oral bioavailability of fenofibrate: in vitro, in vivo and in silico assessments  IF=3.975
O’Shea JP, Faisal W, Ruane-O’Hora T, Devine, KJ, Kostewicz ES, O’Driscolla CM, and, Griffin BT (2015) European J Pharmaceutics and Biopharmaceutics, 96, 207-216.

075 Development of a Physiologically Based Pharmacokinetic/Pharmacodynamic Model to Identify Mechanisms Contributing to Entacapone Low Bioavailability.  IF=2.457
Alqahtani S and Kaddoumi A. (2015) Biopharmaceutics & Drug Disposition, accepted online.

076 Homology Modeling, Molecular Dynamic Simulation and In Silico Screening of Activator for the Intensification of Human Sirtuin Type 1 (SIRT1) By Novel 1, 3, 4-Thiadiazole Derivatives-A Potential Antiaging Approach.  IF=2.457
Saha S, Rai A, and Raj V. (2015) J Bioanal Biomed, Volume 7(4), 97-103.

077 Intestinal solubility and absorption of poorly water soluble compounds: predictions, challenges and solutions. IF=4,87
Fagerberg JH and Bergström CAS. (2015) Therapeutic Delivery online August.

078 Using Cheminformatics in Drug Discovery.  IF=3.872
Lawless MS, Waldman M, Fraczkiewicz R, and Clark RD. (2015) Handbook of Experimental Pharmacology, Springer.

079 Identification of a major radiometabolite of [11C]PBB3. IF=2.529
Hashimotoa H, Kawamuraa K, Takeia M, Igarashia N, Fujishiroa T, Shiomia S, Watanabea R, Mutoa M, Furutsukaa K, Itoa T, Yamasakia T, Yuia J, Nemotoa K, Kimuraa Y, Higuchia M, and Zhanga M-R. (2015) Nuclear Medicine and Biology, accepted online.

080 Physical Stability of Drugs after Storage Above and Below the Glass Transition Temperature: Relationship to Glass-Forming Ability.  IF=1.972
Alhalaweha A, Alzghoulb A, Mahlina D, and Bergström, CAS. (2015) International Journal of Pharmaceuticals, 405(1), 312-317.

081 Marine Drug Discovery Database (MDDD) – A Database of In silico Predicted Physico-Chemical, Drug Likeness and Toxicological Properties of Marine Compounds.   
Sripathy R, Vidya A, Balasubramanian V, Arokiaraj A, Ramchand CN, and Sundararaman M. (2015) Journal of Advanced Bioinformatics Applications and Research, 6(2), 33-44.

082 Discovery of novel S1P2 antagonists. Part 2: Improving the profile of a series of 1,3-bis(aryloxy)benzene derivatives.    IF= 2.486
Kusumia K, Shinozakib K, Yamauraa Y, Hashimotoa A, Kurataa H, Naganawaa A, Uedac H, Otsukia K, Matsushitaa T, Sekiguchia T, Kakuuchia A, and Sekoc T. (2015) Bioorg. Med. Chem. Letters online 8 Sept.

083 1,4-Oxazine beta-secretase (BACE1) inhibitors: from hit generation to orally bioavailable brain penetrant leads.  IF= 3.902
Rombouts FJR, Tresadern G, Delgado O, Lamenca CM, Van Gool M, García-Molina A, De Diego SAA, Oehlrich D, Prokopcova H, Alonso JM, Austin N, Borghys H, Van Brandt S, Surkyn M, De Cleyn M, Vos A, Alexander R, Macdonald GJ, Moechars D, Gijsen HJM, and Trabanco AA. (2015) J. Med. Chem. just accepted.

084 QSAR studies and design of new analogs of vitamin E with enhanced antiproliferative activity on MCF-7 breast cancer cells  IF=2.848
Gagic Z, Nikolic K, Ivkovic B, Filipic S, and Agbaba, D. (2015) J Taiwan Inst Chem Eng August 20 online.

085 Effect of SI-591, a new class of cathepsin K inhibitor with peptidomimetic structure, on bone metabolism in vitro and in vivo  IF=3.736
Fujii T, Ishikawa M, Kubo A, and Tanaka Y. (2015) Bone August 20 online.

 
返回